Laurent Servais Selected Research

Exanthema (Rash)

1/2022

Safety and efficacy of once-daily risdiplam in type 2 and non-ambulant type 3 spinal muscular atrophy (SUNFISH part 2): a phase 3, double-blind, randomised, placebo-controlled trial.

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Laurent Servais Research Topics

Disease

31	Duchenne Muscular Dystrophy (Muscular Dystrophy, Becker) 04/2024 - 01/2014
26	Spinal Muscular Atrophy (Progressive Muscular Atrophy) 02/2024 - 07/2014
7	Muscular Dystrophies (Muscular Dystrophy) 04/2024 - 07/2014
6	Congenital Structural Myopathies (Centronuclear Myopathy) 12/2023 - 11/2017
5	Disease Progression 01/2022 - 05/2015
5	Neuromuscular Diseases (Neuromuscular Disease) 11/2021 - 11/2017
3	Angelman Syndrome (Syndrome, Angelman) 01/2023 - 12/2004
3	Muscular Diseases (Myopathy) 01/2022 - 05/2014
3	Fever (Fevers) 01/2022 - 01/2014
2	Rare Diseases (Rare Disease) 12/2022 - 01/2021
2	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2022 - 08/2011
2	Ataxia (Dyssynergia) 01/2017 - 09/2005
2	Sarcoglycanopathies 09/2015 - 01/2013
2	Cardiomyopathies (Cardiomyopathy) 11/2014 - 11/2014
2	Cerebellar Diseases (Cerebellar Syndrome) 05/2009 - 02/2006
1	Vomiting 04/2024
1	Thrombocytopenia (Thrombopenia) 02/2024
1	Digestive System Diseases 12/2023
1	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 01/2023
1	Nemaline Myopathies (Nemaline Myopathy) 10/2022
1	Exanthema (Rash) 01/2022
1	Aphthous Stomatitis (Aphthous Ulcer) 01/2022
1	Respiratory Insufficiency (Respiratory Failure) 01/2022
1	Urinary Tract Infections (Urinary Tract Infection) 01/2022
1	Pneumonia (Pneumonitis) 01/2022
1	Arthralgia (Joint Pain) 01/2022
1	Muscle Weakness 01/2022
1	Body Weight (Weight, Body) 11/2021
1	Central Nervous System Diseases (CNS Diseases) 10/2021
1	Infections 10/2021
1	Neurodevelopmental Disorders 07/2021
1	Cough 01/2021
1	Neoplasms (Cancer) 01/2020
1	Noonan Syndrome (Female Pseudo-Turner Syndrome) 01/2020
1	Inborn Genetic Diseases (Disease, Hereditary) 03/2018
1	Hearing Loss (Hearing Impairment) 01/2018
1	Myotonic Dystrophy (Dystrophia Myotonica) 01/2017
1	Wasting Syndrome (Wasting Disease) 01/2017
1	Glut1 Deficiency Syndrome 05/2016
1	Rupture 01/2016
1	Brain Diseases (Brain Disorder) 01/2016
1	Chronic Progressive External Ophthalmoplegia (Progressive External Ophthalmoplegia) 01/2016
1	Congenital myasthenic syndrome with episodic apnea 01/2016
1	Infantile onset spinocerebellar ataxia 01/2016
1	Cognitive Dysfunction 01/2016

Drug/Important Bio-Agent (IBA)

12	DystrophinIBA 04/2024 - 01/2014
12	Proteins (Proteins, Gene)FDA Link 12/2023 - 01/2014
12	Biomarkers (Surrogate Marker)IBA 01/2022 - 07/2014
8	RisdiplamIBA 05/2023 - 01/2021
6	ZolgensmaIBA 02/2024 - 10/2021
6	nusinersenIBA 01/2023 - 11/2017
4	MicroRNAs (MicroRNA)IBA 11/2020 - 01/2013
3	golodirsenIBA 01/2022 - 01/2020
2	Adrenal Cortex Hormones (Corticosteroids)IBA 04/2024 - 01/2018
2	GlucocorticoidsIBA 03/2024 - 01/2022
2	Coenzyme A (CoA)IBA 01/2024 - 01/2022
2	RNA Precursors (Precursor, mRNA)IBA 05/2023 - 12/2022
2	Antisense OligonucleotidesIBA 01/2021 - 06/2020
2	MyostatinIBA 06/2020 - 11/2017
2	PRO051IBA 10/2014 - 01/2014
2	Ethanol (Ethyl Alcohol)IBA 05/2009 - 09/2005
1	givinostatIBA 04/2024
1	Troponin IIBA 02/2024
1	Tamoxifen FDA LinkGeneric 10/2023
1	viltolarsenIBA 01/2023
1	Immunoglobulin A (IgA)IBA 01/2023
1	Insulin (Novolin)FDA Link 01/2023
1	mesoglycanIBA 10/2021
1	Alanine Transaminase (SGPT)IBA 10/2021
1	UbiquitinIBA 07/2021
1	CholesterolIBA 01/2021
1	idebenoneIBA 01/2020
1	Growth Hormone (Somatotropin)IBA 01/2020
1	UridineIBA 03/2018
1	Ferritins (Ferritin)IBA 01/2018
1	IronIBA 01/2018
1	myotubularinIBA 11/2017
1	salicylhydroxamic acid (SHAM)IBA 11/2017
1	Amino Acid Transport System X-AG (Glutamate Transporter)IBA 01/2017
1	RNA (Ribonucleic Acid)IBA 01/2017
1	Therapeutic UsesIBA 05/2016
1	triheptanoinIBA 05/2016
1	Nitric Oxide Synthase Type I (Neuronal Nitric Oxide Synthase)IBA 01/2016
1	Mitochondrial DNA (mtDNA)IBA 01/2016
1	Cholinergic Agents (Cholinergics)IBA 01/2016
1	Ryanodine Receptor Calcium Release Channel (Ryanodine Receptor)IBA 01/2016
1	Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)IBA 01/2016
1	choline transporterIBA 01/2016
1	Matrix Metalloproteinase 9 (Gelatinase B)IBA 05/2015

Therapy/Procedure

17	Therapeutics 12/2023 - 11/2009
3	Mechanical Ventilators (Ventilator) 12/2023 - 01/2021
2	Wearable Electronic Devices 01/2024 - 01/2021
1	Artificial Respiration (Mechanical Ventilation) 01/2022
1	Gastrostomy 01/2022
1	Investigational Therapies (Experimental Therapy) 05/2021
1	Aftercare (After-Treatment) 01/2020
1	Hearing Aids (Hearing Aid) 01/2018
1	Ketogenic Diet 05/2016
1	Epidural Anesthesia 01/2016
1	Noninvasive Ventilation 01/2015